- 产品信息
商品描述
靶点-Target
EAAT3
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EAAT3. AA range:122-171
特异性
EAAT3 Polyclonal Antibody detects endogenous levels of EAAT3 protein.
基因名称
SLC1A1
蛋白名称
Excitatory amino acid transporter 3
别名
SLC1A1;EAAC1;EAAT3;Excitatory amino acid transporter 3;Excitatory amino-acid carrier 1;Neuronal and epithelial glutamate transporter;Sodium-dependent glutamate/aspartate transporter 3;Solute carrier family 1 member 1
Organism-1
Human
基因ID-1
6505
SwissProt-1
P43005
Organism-2
Mouse
基因ID-2
20510
SwissProt-2
P51906
Organism-3
Rat
基因ID-3
25550
SwissProt-3
P51907
背景
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010],
细胞定位
Cell membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome . Early endosome membrane . Late endosome membrane . Recycling endosome membrane .





