FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
E2F-5
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human E2F-5. AA range:93-142
特异性
E2F-5 Polyclonal Antibody detects endogenous levels of E2F-5 protein.
基因名称
E2F5
蛋白名称
Transcription factor E2F5
别名
E2F5;Transcription factor E2F5;E2F-5
Organism-1
Human
基因ID-1
1875
SwissProt-1
Q15329
Organism-2
Mouse
基因ID-2
13559
SwissProt-2
Q61502
Organism-3
Rat
SwissProt-3
Q62814
背景
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 inter
细胞定位
Nucleus.
