- 产品信息
商品描述
靶点-Target
Dyrk1B
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DYR1B. AA range:331-380
特异性
Dyrk1B Polyclonal Antibody detects endogenous levels of Dyrk1B protein.
基因名称
DYRK1B
蛋白名称
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
别名
DYRK1B;MIRK;Dual specificity tyrosine-phosphorylation-regulated kinase 1B;Minibrain-related kinase;Mirk protein kinase
Organism-1
Human
基因ID-1
9149
SwissProt-1
Q9Y463
Organism-2
Mouse
基因ID-2
13549
SwissProt-2
Q9Z188
背景
This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
细胞定位
Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of double-strand breaks (DSBs) following DNA damage. .





