FGF-2 Polyclonal Antibody
¥680.00
Dynactin 2 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2613835
- 产品信息
商品描述
靶点-Target
Dynactin 2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human p50 Dynamitin. AA range:341-390
特异性
Dynactin 2 Polyclonal Antibody detects endogenous levels of Dynactin 2 protein.
基因名称
DCTN2
蛋白名称
Dynactin subunit 2
别名
DCTN2;DCTN50;Dynactin subunit 2;50 kDa dynein-associated polypeptide;Dynactin complex 50 kDa subunit;DCTN-50;p50 dynamitin
Organism-1
Human
基因ID-1
10540
SwissProt-1
Q13561
Organism-2
Mouse
基因ID-2
69654
SwissProt-2
Q99KJ8
Organism-3
Rat
基因ID-3
299850
SwissProt-3
Q6AYH5
背景
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Membrane ; Peripheral membrane protein .
