FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Dvl-2
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Dvl-2 . at AA range: 670-750
特异性
Dvl-2 Polyclonal Antibody detects endogenous levels of Dvl-2 protein.
基因名称
DVL2
蛋白名称
Segment polarity protein dishevelled homolog DVL-2
别名
DVL2;Segment polarity protein dishevelled homolog DVL-2;Dishevelled-2;DSH homolog 2
Organism-1
Human
基因ID-1
1856
SwissProt-1
O14641
Organism-2
Mouse
基因ID-2
13543
SwissProt-2
Q60838
背景
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol . Cytoplasmic vesicle . Nucleus . Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta (By similarity). Interaction with FOXK1 and FOXK2 induces nuclear translocation (PubMed:25805136). .
