FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Duffy
反应性
Human,Mouse
应用
IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
36kD
推荐稀释比
IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DARC. AA range:1-50
特异性
Duffy Polyclonal Antibody detects endogenous levels of Duffy protein.
基因名称
DARC
蛋白名称
Duffy antigen/chemokine receptor
别名
DARC;FY;GPD;Duffy antigen/chemokine receptor;Fy glycoprotein;GpFy;Glycoprotein D;Plasmodium vivax receptor;CD antigen CD234
Organism-1
Human
基因ID-1
2532
SwissProt-1
Q16570
Organism-2
Mouse
SwissProt-2
Q9QUI6
背景
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Early endosome. Recycling endosome. Membrane; Multi-pass membrane protein. Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane.
