- 产品信息
商品描述
靶点-Target
Dsg2
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
140kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450
特异性
Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.
基因名称
DSG2
蛋白名称
Desmoglein-2
别名
DSG2;CDHF5;Desmoglein-2;Cadherin family member 5;HDGC
Organism-1
Human
基因ID-1
1829
SwissProt-1
Q14126
Organism-2
Mouse
SwissProt-2
O55111
背景
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],
细胞定位
Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome.





