FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Dsg1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
114kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DSG1. AA range:161-210
特异性
Dsg1 Polyclonal Antibody detects endogenous levels of Dsg1 protein.
基因名称
DSG1
蛋白名称
Desmoglein-1
别名
DSG1;CDHF4;Desmoglein-1;Cadherin family member 4;Desmosomal glycoprotein 1;DG1;DGI;Pemphigus foliaceus antigen
Organism-1
Human
基因ID-1
1828
SwissProt-1
Q02413
背景
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome.
