DSCR 1 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

一键复制产品信息
产品规格:
  • 50μL
  • 100μL
货号:

FAB2613825

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    DSCR 1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    22kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250

  • 特异性

    DSCR 1 Polyclonal Antibody detects endogenous levels of DSCR 1 protein.

  • 基因名称

    RCAN1

  • 蛋白名称

    Calcipressin-1

  • 别名

    RCAN1;ADAPT78;CSP1;DSC1;DSCR1;Calcipressin-1;Adapt78;Down syndrome critical region protein 1;Myocyte-enriched calcineurin-interacting protein 1;MCIP1;Regulator of calcineurin 1

  • Organism-1

    Human

  • 基因ID-1

    1827

  • SwissProt-1

    P53805

  • Organism-2

    Mouse

  • 基因ID-2

    54720

  • SwissProt-2

    Q9JHG6

  • Organism-3

    Rat

  • 基因ID-3

    266766

  • SwissProt-3

    Q6IN33

  • 背景

    The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],

  • 细胞定位

    intracellular,nucleus,cytoplasm,