- 产品信息
商品描述
靶点-Target
DSCR 1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250
特异性
DSCR 1 Polyclonal Antibody detects endogenous levels of DSCR 1 protein.
基因名称
RCAN1
蛋白名称
Calcipressin-1
别名
RCAN1;ADAPT78;CSP1;DSC1;DSCR1;Calcipressin-1;Adapt78;Down syndrome critical region protein 1;Myocyte-enriched calcineurin-interacting protein 1;MCIP1;Regulator of calcineurin 1
Organism-1
Human
基因ID-1
1827
SwissProt-1
P53805
Organism-2
Mouse
基因ID-2
54720
SwissProt-2
Q9JHG6
Organism-3
Rat
基因ID-3
266766
SwissProt-3
Q6IN33
背景
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],
细胞定位
intracellular,nucleus,cytoplasm,





