FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Dorfin
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RNF19A. AA range:51-100
特异性
Dorfin Polyclonal Antibody detects endogenous levels of Dorfin protein.
基因名称
RNF19A
蛋白名称
E3 ubiquitin-protein ligase RNF19A
别名
RNF19A;RNF19;E3 ubiquitin-protein ligase RNF19A;Double ring-finger protein;Dorfin;RING finger protein 19A;p38
Organism-1
Human
基因ID-1
25897
SwissProt-1
Q9NV58
Organism-2
Mouse
基因ID-2
30945
SwissProt-2
P50636
背景
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
Membrane ; Multi-pass membrane protein . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Present in the hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients.
