FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DOCK 2
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
212kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human DOCK 2.
特异性
DOCK 2 Polyclonal Antibody detects endogenous levels of DOCK 2 protein.
基因名称
DOCK2
蛋白名称
Dedicator of cytokinesis protein 2
别名
DOCK2;KIAA0209;Dedicator of cytokinesis protein 2
Organism-1
Human
基因ID-1
1794
SwissProt-1
Q92608
Organism-2
Mouse
基因ID-2
94176
SwissProt-2
Q8C3J5
背景
The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],
细胞定位
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Colocalizes with F-actin.
