FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DOCK 180
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
215kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710
特异性
DOCK 180 Polyclonal Antibody detects endogenous levels of DOCK 180 protein.
基因名称
DOCK1
蛋白名称
Dedicator of cytokinesis protein 1
别名
DOCK1;Dedicator of cytokinesis protein 1;180 kDa protein downstream of CRK;DOCK180
Organism-1
Human
基因ID-1
1793
SwissProt-1
Q14185
Organism-2
Mouse
基因ID-2
330662
SwissProt-2
Q8BUR4
背景
This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
细胞定位
Cytoplasm . Membrane . Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate. .
