FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Dnmt3b
反应性
Human,Chicken(testedbyourcustomer）
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
96kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DNMT3B. AA range:1-50
特异性
Dnmt3b Polyclonal Antibody detects endogenous levels of Dnmt3b protein.
基因名称
DNMT3B
蛋白名称
DNA (cytosine-5)-methyltransferase 3B
别名
DNMT3B;DNA;cytosine-5;-methyltransferase 3B;Dnmt3b;DNA methyltransferase HsaIIIB;DNA MTase HsaIIIB;M.HsaIIIB
Organism-1
Human
基因ID-1
1789
SwissProt-1
Q9UBC3
Organism-2
Mouse
SwissProt-2
O88509
背景
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011],
细胞定位
Nucleus .
