FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DnaJB4
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DNAJB4. AA range:91-140
特异性
DnaJB4 Polyclonal Antibody detects endogenous levels of DnaJB4 protein.
基因名称
DNAJB4
蛋白名称
DnaJ homolog subfamily B member 4
别名
DNAJB4;DNAJW;HLJ1;DnaJ homolog subfamily B member 4;Heat shock 40 kDa protein 1 homolog;HSP40 homolog;Heat shock protein 40 homolog;Human liver DnaJ-like protein
Organism-1
Human
基因ID-1
11080
SwissProt-1
Q9UDY4
Organism-2
Mouse
基因ID-2
67035
SwissProt-2
Q9D832
背景
The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
细胞定位
Cytoplasm . Cell membrane . Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
