FGF-2 Polyclonal Antibody
¥680.00
DNA pol δ Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2613788
- 产品信息
商品描述
靶点-Target
DNA pol δ cat
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110 124kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human POLD1. AA range:1051-1100
特异性
DNA pol δ cat Polyclonal Antibody detects endogenous levels of DNA pol δ cat protein.
基因名称
POLD1
蛋白名称
DNA polymerase delta catalytic subunit
别名
POLD1;POLD;DNA polymerase delta catalytic subunit;DNA polymerase subunit delta p125
Organism-1
Human
基因ID-1
5424
SwissProt-1
P28340
Organism-2
Mouse
基因ID-2
18971
SwissProt-2
P52431
Organism-3
Rat
基因ID-3
59294
SwissProt-3
O54747
背景
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012],
细胞定位
Nucleus . Colocalizes with PCNA and POLD3 at S phase replication sites (PubMed:11595739). After UV irradiation, recruited to DNA damage sites within 2 hours, independently on the cell cycle phase, nor on PCNA ubiquitination. This recruitment requires POLD3, PCNA and RFC1-replication factor C complex (PubMed:20227374, PubMed:22801543). .
