DNA Ligase I Polyclonal Antibody一抗_现货

靶点-Target
DNA Ligase I
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
133kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DNL1. AA range:111-160
特异性
DNA Ligase I Polyclonal Antibody detects endogenous levels of DNA Ligase I protein.
基因名称
LIG1
蛋白名称
DNA ligase 1
别名
LIG1;DNA ligase 1;DNA ligase I;Polydeoxyribonucleotide synthase [ATP] 1
Organism-1
Human
基因ID-1
3978
SwissProt-1
P18858
Organism-2
Mouse
SwissProt-2
P37913
背景
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
细胞定位
Nucleus.

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DNA Ligase I Polyclonal Antibody