FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DMGDH
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
97kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866
特异性
DMGDH Polyclonal Antibody detects endogenous levels of DMGDH protein.
基因名称
DMGDH
蛋白名称
Dimethylglycine dehydrogenase mitochondrial
别名
DMGDH;Dimethylglycine dehydrogenase;mitochondrial;ME2GLYDH
Organism-1
Human
基因ID-1
29958
SwissProt-1
Q9UI17
Organism-2
Mouse
SwissProt-2
Q9DBT9
背景
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
Mitochondrion.
