FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DLC-1
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
123kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RHG07. AA range:61-110
特异性
DLC-1 Polyclonal Antibody detects endogenous levels of DLC-1 protein.
基因名称
DLC1
蛋白名称
Rho GTPase-activating protein 7
别名
DLC1;ARHGAP7;KIAA1723;STARD12;Rho GTPase-activating protein 7;Deleted in liver cancer 1 protein;DLC-1;HP protein;Rho-type GTPase-activating protein 7;START domain-containing protein 12;StARD12;StAR-related lipid transfer protein
Organism-1
Human
基因ID-1
10395
SwissProt-1
Q96QB1
Organism-2
Mouse
基因ID-2
50768
SwissProt-2
Q9R0Z9
Organism-3
Rat
SwissProt-3
Q63744
背景
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010],
细胞定位
Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
