FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DGK-δ
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
135kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DGKD. AA range:41-90
特异性
DGK-δ Polyclonal Antibody detects endogenous levels of DGK-δ protein.
基因名称
DGKD
蛋白名称
Diacylglycerol kinase delta
别名
DGKD;KIAA0145;Diacylglycerol kinase delta;DAG kinase delta;130 kDa diacylglycerol kinase;Diglyceride kinase delta;DGK-delta
Organism-1
Human
基因ID-1
8527
SwissProt-1
Q16760
背景
This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Membrane, clathrin-coated pit . Cytoplasm .; [Isoform 1]: Cell membrane ; Peripheral membrane protein . Cytoplasm . Isoform 1 translocation from cytoplasm to the plasma membrane is induced by phorbol esters (PubMed:12200442). Phorbol esters induce the conversion into the monomeric form which can translocate to the plasma membrane (PubMed:12084710). .
