- 产品信息
商品描述
靶点-Target
DGK-β
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DGKB. AA range:657-706
特异性
DGK-β Polyclonal Antibody detects endogenous levels of DGK-β protein.
基因名称
DGKB
蛋白名称
Diacylglycerol kinase beta
别名
DGKB;DAGK2;KIAA0718;Diacylglycerol kinase beta;DAG kinase beta;90 kDa diacylglycerol kinase;Diglyceride kinase beta;DGK-beta
Organism-1
Human
基因ID-1
1607
SwissProt-1
Q9Y6T7
Organism-2
Mouse
基因ID-2
217480
SwissProt-2
Q6NS52
Organism-3
Rat
基因ID-3
54248
SwissProt-3
P49621
背景
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, synapse, postsynaptic cell membrane ; Peripheral membrane protein . Cell membrane ; Peripheral membrane protein . Cytoplasm . Translocation to the plasma membrane is induced by phorbol esters. .; [Isoform 2]: Cytoplasm .





