FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Dexras2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
35kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RASD2. AA range:217-266
特异性
Dexras2 Polyclonal Antibody detects endogenous levels of Dexras2 protein.
基因名称
RASD2
蛋白名称
GTP-binding protein Rhes
别名
RASD2;TEM2;GTP-binding protein Rhes;Ras homolog enriched in striatum;Tumor endothelial marker 2
Organism-1
Human
基因ID-1
23551
SwissProt-1
Q96D21
Organism-2
Mouse
基因ID-2
75141
SwissProt-2
P63032
Organism-3
Rat
基因ID-3
171099
SwissProt-3
P63033
背景
This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016],
细胞定位
Cell membrane ; Lipid-anchor .
