Defensin α1 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613739

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商品描述
  • 靶点-Target

    DEF1

  • 反应性

    Human,Mouse

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    11kD

  • 推荐稀释比

    IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Defensin alpha1. AA range:3-52

  • 特异性

    Defensin α1 Polyclonal Antibody detects endogenous levels of Defensin α1 protein.

  • 基因名称

    DEFA1

  • 蛋白名称

    Neutrophil defensin 1

  • 别名

    DEFA1;DEF1;DEFA2;MRS;DEFA1B;Neutrophil defensin 1;Defensin;alpha 1;HNP-1;HP-1;HP1

  • Organism-1

    Human

  • 基因ID-1

    1667

  • SwissProt-1

    P59665

  • 背景

    defensin alpha 1(DEFA1) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014],

  • 细胞定位

    Secreted.