- 产品信息
商品描述
靶点-Target
DcR3
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TNFRSF6B. AA range:251-300
特异性
DcR3 Polyclonal Antibody detects endogenous levels of DcR3 protein.
基因名称
TNFRSF6B
蛋白名称
Tumor necrosis factor receptor superfamily member 6B
别名
TNFRSF6B;DCR3;TR6;Tumor necrosis factor receptor superfamily member 6B;Decoy receptor 3;DcR3;Decoy receptor for Fas ligand;M68
Organism-1
Human
基因ID-1
8771
SwissProt-1
O95407
背景
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011],
细胞定位
Secreted.





