FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DCAMKL2
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
83kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DCLK2. AA range:1-50
特异性
DCAMKL2 Polyclonal Antibody detects endogenous levels of DCAMKL2 protein.
基因名称
DCLK2
蛋白名称
Serine/threonine-protein kinase DCLK2
别名
DCLK2;DCAMKL2;DCDC3B;DCK2;Serine/threonine-protein kinase DCLK2;CaMK-like CREB regulatory kinase 2;CL2;CLICK-II;CLICK2;Doublecortin domain-containing protein 3B;Doublecortin-like and CAM kinase-like 2;Doublecortin-like kinase 2
Organism-1
Human
基因ID-1
166614
SwissProt-1
Q8N568
Organism-2
Mouse
基因ID-2
70762
SwissProt-2
Q6PGN3
背景
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alterna
细胞定位
Cytoplasm, cytoskeleton. Colocalizes with microtubules. .
