- 产品信息
商品描述
靶点-Target
DARPP-32
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DARPP-32. AA range:41-90
特异性
DARPP-32 Polyclonal Antibody detects endogenous levels of DARPP-32 protein.
基因名称
PPP1R1B
蛋白名称
Protein phosphatase 1 regulatory subunit 1B
别名
PPP1R1B;DARPP32;Protein phosphatase 1 regulatory subunit 1B;DARPP-32;Dopamine- and cAMP-regulated neuronal phosphoprotein
Organism-1
Human
基因ID-1
84152
SwissProt-1
Q9UD71
Organism-2
Mouse
基因ID-2
19049
SwissProt-2
Q60829
Organism-3
Rat
基因ID-3
360616
SwissProt-3
Q6J4I0
背景
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Cytoplasm.





