FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DAP-5
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EIF4G2. AA range:41-90
特异性
DAP-5 Polyclonal Antibody detects endogenous levels of DAP-5 protein.
基因名称
EIF4G2
蛋白名称
Eukaryotic translation initiation factor 4 gamma 2
别名
EIF4G2;DAP5;OK/SW-cl.75;Eukaryotic translation initiation factor 4 gamma 2;eIF-4-gamma 2;eIF-4G 2;eIF4G 2;Death-associated protein 5;DAP-5;p97
Organism-1
Human
基因ID-1
1982
SwissProt-1
P78344
Organism-2
Mouse
基因ID-2
13690
SwissProt-2
Q62448
背景
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008],
细胞定位
cytosol,cell-cell adherens junction,membrane,eukaryotic translation initiation factor 4F complex,axon,
