- 产品信息
商品描述
靶点-Target
D4DR
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404
特异性
D4DR Polyclonal Antibody detects endogenous levels of D4DR protein.
基因名称
DRD4
蛋白名称
D(4) dopamine receptor
别名
DRD4;D;4;dopamine receptor;D;2C;dopamine receptor;Dopamine D4 receptor
Organism-1
Human
基因ID-1
1815
SwissProt-1
P21917
Organism-2
Mouse
基因ID-2
13491
SwissProt-2
P51436
Organism-3
Rat
基因ID-3
25432
SwissProt-3
P30729
背景
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .





