Cytokeratin 8 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613697

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商品描述
  • 靶点-Target

    Cytokeratin 8

  • 反应性

    Human,Mouse,Monkey

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    52kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Keratin 8. AA range:41-90

  • 特异性

    Cytokeratin 8 Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein.

  • 基因名称

    KRT8

  • 蛋白名称

    Keratin type II cytoskeletal 8

  • 别名

    KRT8;CYK8;Keratin;type II cytoskeletal 8;Cytokeratin-8;CK-8;Keratin-8;K8;Type-II keratin Kb8

  • Organism-1

    Human

  • 基因ID-1

    3856

  • SwissProt-1

    P05787

  • Organism-2

    Mouse

  • 基因ID-2

    16691

  • SwissProt-2

    P11679

  • 背景

    keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

  • 细胞定位

    Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .