FGF-2 Polyclonal Antibody
¥680.00
Cystatin B Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2613675
- 产品信息
商品描述
靶点-Target
Cystatin B
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
11kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Stefin B. AA range:49-98
特异性
Cystatin B Polyclonal Antibody detects endogenous levels of Cystatin B protein.
基因名称
CSTB
蛋白名称
Cystatin-B
别名
CSTB;CST6;STFB;Cystatin-B;CPI-B;Liver thiol proteinase inhibitor;Stefin-B
Organism-1
Human
基因ID-1
1476
SwissProt-1
P04080
Organism-2
Mouse
SwissProt-2
Q62426
Organism-3
Rat
基因ID-3
25308
SwissProt-3
P01041
背景
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG rep
细胞定位
Cytoplasm . Nucleus .
