FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CysLTR1
反应性
Human,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CLTR1. AA range:131-180
特异性
CysLTR1 Polyclonal Antibody detects endogenous levels of CysLTR1 protein.
基因名称
CYSLTR1
蛋白名称
Cysteinyl leukotriene receptor 1
别名
CYSLTR1;CYSLT1;Cysteinyl leukotriene receptor 1;CysLTR1;Cysteinyl leukotriene D4 receptor;LTD4 receptor;G-protein coupled receptor HG55;HMTMF81
Organism-1
Human
基因ID-1
10800
SwissProt-1
Q9Y271
Organism-2
Mouse
SwissProt-2
Q99JA4
背景
This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
细胞定位
Cell membrane; Multi-pass membrane protein.
