FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CYP8B1
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 8B1. AA range:371-420
特异性
CYP8B1 Polyclonal Antibody detects endogenous levels of CYP8B1 protein.
基因名称
CYP8B1
蛋白名称
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
别名
CYP8B1;CYP12;7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase;7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase;CYPVIIIB1;Cytochrome P450 8B1;Sterol 12-alpha-hydroxylase
Organism-1
Human
基因ID-1
1582
SwissProt-1
Q9UNU6
Organism-2
Mouse
基因ID-2
13124
SwissProt-2
O88962
背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
