- 产品信息
商品描述
靶点-Target
CYP2R1
反应性
Human,Mouse,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CYP2R1. AA range:251-300
特异性
CYP2R1 Polyclonal Antibody detects endogenous levels of CYP2R1 protein.
基因名称
CYP2R1
蛋白名称
Vitamin D 25-hydroxylase
别名
CYP2R1;Vitamin D 25-hydroxylase;Cytochrome P450 2R1
Organism-1
Human
基因ID-1
120227
SwissProt-1
Q6VVX0
Organism-2
Mouse
基因ID-2
244209
SwissProt-2
Q6VVW9
背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.





