CYP2C8/9/18/19 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613643

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商品描述
  • 靶点-Target

    CYP2C8/9/18/19

  • 反应性

    Human

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    60kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2C8/9/18/19. AA range:111-160

  • 特异性

    CYP2C8/9/18/19 Polyclonal Antibody detects endogenous levels of CYP2C8/9/18/19 protein.

  • 基因名称

    CYP2C8/9/18/19

  • 蛋白名称

    Cytochrome P450 2C8/9/18/19

  • 别名

    CYP2C8;Cytochrome P450 2C8;CYPIIC8;Cytochrome P450 IIC2;Cytochrome P450 MP-12;Cytochrome P450 MP-20;Cytochrome P450 form 1;S-mephenytoin 4-hydroxylase;CYP2C9;CYP2C10;Cytochrome P450 2C9;R;-limonene 6-monooxygenase;S;-limonene

  • Organism-1

    Human

  • 基因ID-1

    1562;1558;1559;1557

  • SwissProt-1

    P10632;P11712;P33260;P33261

  • 背景

    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],

  • 细胞定位

    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.