- 产品信息
商品描述
靶点-Target
CYP2C8
反应性
Human
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
56kD
推荐稀释比
IHC: 1:100-1:300;IF 1:50-200;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CYP2C8. AA range:241-290
特异性
CYP2C8 Polyclonal Antibody detects endogenous levels of CYP2C8 protein.
基因名称
CYP2C8
蛋白名称
Cytochrome P450 2C8
别名
CYP2C8;Cytochrome P450 2C8;CYPIIC8;Cytochrome P450 IIC2;Cytochrome P450 MP-12;Cytochrome P450 MP-20;Cytochrome P450 form 1;S-mephenytoin 4-hydroxylase
Organism-1
Human
基因ID-1
1558
SwissProt-1
P10632
背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],
细胞定位
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.





