FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CYP21A2
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 21A2. AA range:151-200
特异性
CYP21A2 Polyclonal Antibody detects endogenous levels of CYP21A2 protein.
基因名称
CYP21A2
蛋白名称
Steroid 21-hydroxylase
别名
CYP21A2;CYP21;CYP21B;Steroid 21-hydroxylase;21-OHase;Cytochrome P-450c21;Cytochrome P450 21;Cytochrome P450 XXI;Cytochrome P450-C21;Cytochrome P450-C21B
Organism-1
Human
基因ID-1
1589
SwissProt-1
P08686
Organism-2
Mouse
SwissProt-2
P03940
背景
cytochrome P450 family 21 subfamily A member 2(CYP21A2) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane; Peripheral membrane protein . Microsome membrane ; Peripheral membrane protein .
