FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CYP1A1/2
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 1A1/2. AA range:71-120
特异性
CYP1A1/2 Polyclonal Antibody detects endogenous levels of CYP1A1/2 protein.
基因名称
CYP1A1/CYP1A2
蛋白名称
Cytochrome P450 1A1/2
别名
CYP1A1;Cytochrome P450 1A1;CYPIA1;Cytochrome P450 form 6;Cytochrome P450-C;Cytochrome P450-P1;CYP1A2;Cytochrome P450 1A2;CYPIA2;Cytochrome P;3;450;Cytochrome P450 4;Cytochrome P450-P3
Organism-1
Human
基因ID-1
1543;1544
SwissProt-1
P04798;P05177
Organism-2
Mouse
基因ID-2
13076;13077
Organism-3
Rat
基因ID-3
24296;24297
SwissProt-3
P00185;P04799
背景
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016],
细胞定位
Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion inner membrane ; Peripheral membrane protein . Microsome membrane ; Peripheral membrane protein . Cytoplasm .
