CYP11B1/2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613618

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商品描述
  • 靶点-Target

    CYP11B1/2

  • 反应性

    Human

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    57kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from the C-terminal region of human CYP11B1/2.

  • 特异性

    CYP11B1/2 Polyclonal Antibody detects endogenous levels of CYP11B1/2 protein.

  • 基因名称

    CYP11B1/CYP11B2

  • 蛋白名称

    Cytochrome P450 11B1 mitochondrial/Cytochrome P450 11B2 mitochondrial

  • 别名

    CYP11B1;S11BH;Cytochrome P450 11B1;mitochondrial;CYPXIB1;Cytochrome P-450c11;Cytochrome P450C11;Steroid 11-beta-hydroxylase;CYP11B2;Cytochrome P450 11B2, mitochondrial;Aldosterone synthase;ALDOS;Aldosterone-synthesizing enzyme;

  • Organism-1

    Human

  • 基因ID-1

    1584;1585

  • SwissProt-1

    P15538;P19099

  • 背景

    cytochrome P450 family 11 subfamily B member 1(CYP11B1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Mitochondrion inner membrane ; Peripheral membrane protein .