- 产品信息
商品描述
靶点-Target
CYP11A1
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 11A1. AA range:412-461
特异性
CYP11A1 Polyclonal Antibody detects endogenous levels of CYP11A1 protein.
基因名称
CYP11A1
蛋白名称
Cholesterol side-chain cleavage enzyme mitochondrial
别名
CYP11A1;CYP11A;Cholesterol side-chain cleavage enzyme;mitochondrial;CYPXIA1;Cholesterol desmolase;Cytochrome P450 11A1;Cytochrome P450;scc;
Organism-1
Human
基因ID-1
1583
SwissProt-1
P05108
Organism-2
Mouse
SwissProt-2
Q9QZ82
背景
cytochrome P450 family 11 subfamily A member 1(CYP11A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein . Localizes to the matrix side of the mitochondrion inner membrane. .





