FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CUG-BP1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CELF-1. AA range:71-120
特异性
CUG-BP1 Polyclonal Antibody detects endogenous levels of CUG-BP1 protein.
基因名称
CELF1
蛋白名称
CUGBP Elav-like family member 1
别名
CELF1;BRUNOL2;CUGBP;CUGBP1;NAB50;CUGBP Elav-like family member 1;CELF-1;50 kDa nuclear polyadenylated RNA-binding protein;Bruno-like protein 2;CUG triplet repeat RNA-binding protein 1;CUG-BP1;CUG-BP- and ETR-3-like factor 1;Dead
Organism-1
Human
基因ID-1
10658
SwissProt-1
Q92879
Organism-2
Mouse
基因ID-2
13046
SwissProt-2
P28659
Organism-3
Rat
基因ID-3
362160
SwissProt-3
Q4QQT3
背景
CUGBP, Elav-like family member 1(CELF1) Homo sapiens Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
