FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CRSP150
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
161kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MED14. AA range:701-750
特异性
CRSP150 Polyclonal Antibody detects endogenous levels of CRSP150 protein.
基因名称
MED14
蛋白名称
Mediator of RNA polymerase II transcription subunit 14
别名
MED14;ARC150;CRSP2;CXorf4;DRIP150;EXLM1;RGR1;TRAP170;Mediator of RNA polymerase II transcription subunit 14;Activator-recruited cofactor 150 kDa component;ARC150;Cofactor required for Sp1 transcriptional activation subunit 2;CRS
Organism-1
Human
基因ID-1
9282
SwissProt-1
O60244
Organism-2
Mouse
基因ID-2
26896
SwissProt-2
A2ABV5
背景
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .
