FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CRMP-3
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140
特异性
CRMP-3 Polyclonal Antibody detects endogenous levels of CRMP-3 protein.
基因名称
DPYSL4
蛋白名称
Dihydropyrimidinase-related protein 4
别名
DPYSL4;CRMP3;ULIP4;Dihydropyrimidinase-related protein 4;DRP-4;Collapsin response mediator protein 3;CRMP-3;UNC33-like phosphoprotein 4;ULIP-4
Organism-1
Human
基因ID-1
10570
SwissProt-1
O14531
Organism-2
Mouse
SwissProt-2
O35098
Organism-3
Rat
基因ID-3
25417
SwissProt-3
Q62951
背景
disease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer.,function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.,
细胞定位
Cytoplasm .
