FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CRF-RII
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CRHR2. AA range:71-120
特异性
CRF-RII Polyclonal Antibody detects endogenous levels of CRF-RII protein.
基因名称
CRHR2
蛋白名称
Corticotropin-releasing factor receptor 2
别名
CRHR2;CRF2R;CRH2R;Corticotropin-releasing factor receptor 2;CRF-R-2;CRF-R2;CRFR-2;Corticotropin-releasing hormone receptor 2;CRH-R-2;CRH-R2
Organism-1
Human
基因ID-1
1395
SwissProt-1
Q13324
Organism-2
Mouse
SwissProt-2
Q60748
Organism-3
Rat
基因ID-3
64680
SwissProt-3
P47866
背景
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011],
细胞定位
Cell membrane ; Multi-pass membrane protein .
