- 产品信息
商品描述
靶点-Target
CREM
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
34kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CREM. AA range:81-130
特异性
CREM Polyclonal Antibody detects endogenous levels of CREM protein.
基因名称
CREM
蛋白名称
cAMP-responsive element modulator
别名
CREM;cAMP-responsive element modulator;Inducible cAMP early repressor;ICER
Organism-1
Human
基因ID-1
1390
SwissProt-1
Q03060
Organism-2
Mouse
基因ID-2
12916
SwissProt-2
P27699
Organism-3
Rat
基因ID-3
25620
SwissProt-3
Q03061
背景
cAMP responsive element modulator(CREM) Homo sapiens This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.; [Isoform 6]: Cytoplasm . Nucleus .





