CREM Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613551

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商品描述
  • 靶点-Target

    CREM

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    34kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human CREM. AA range:81-130

  • 特异性

    CREM Polyclonal Antibody detects endogenous levels of CREM protein.

  • 基因名称

    CREM

  • 蛋白名称

    cAMP-responsive element modulator

  • 别名

    CREM;cAMP-responsive element modulator;Inducible cAMP early repressor;ICER

  • Organism-1

    Human

  • 基因ID-1

    1390

  • SwissProt-1

    Q03060

  • Organism-2

    Mouse

  • 基因ID-2

    12916

  • SwissProt-2

    P27699

  • Organism-3

    Rat

  • 基因ID-3

    25620

  • SwissProt-3

    Q03061

  • 背景

    cAMP responsive element modulator(CREM) Homo sapiens This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus.; [Isoform 6]: Cytoplasm . Nucleus .