- 产品信息
商品描述
靶点-Target
CPN cat
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
total 52kD,Cleaved 48kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CPN1. AA range:409-458
特异性
CPN cat Polyclonal Antibody detects endogenous levels of CPN cat protein.
基因名称
CPN1
蛋白名称
Carboxypeptidase N catalytic chain
别名
CPN1;ACBP;Carboxypeptidase N catalytic chain;CPN;Anaphylatoxin inactivator;Arginine carboxypeptidase;Carboxypeptidase N polypeptide 1;Carboxypeptidase N small subunit;Kininase-1;Lysine carboxypeptidase;Plasma carboxypeptidase B;S
Organism-1
Human
基因ID-1
1369
SwissProt-1
P15169
Organism-2
Mouse
SwissProt-2
Q9JJN5
背景
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space.





