- 产品信息
商品描述
靶点-Target
COX4I2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
20kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human COX42. AA range:31-80
特异性
COX4I2 Polyclonal Antibody detects endogenous levels of COX4I2 protein.
基因名称
COX4I2
蛋白名称
Cytochrome c oxidase subunit 4 isoform 2 mitochondrial
别名
COX4I2;COX4L2;Cytochrome c oxidase subunit 4 isoform 2;mitochondrial;Cytochrome c oxidase subunit IV isoform 2;COX IV-2
Organism-1
Human
基因ID-1
84701
SwissProt-1
Q96KJ9
Organism-2
Mouse
基因ID-2
84682
SwissProt-2
Q91W29
Organism-3
Rat
基因ID-3
84683
SwissProt-3
Q91Y94
背景
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .





