FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
COX10
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
49kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human COX10. AA range:98-147
特异性
COX10 Polyclonal Antibody detects endogenous levels of COX10 protein.
基因名称
COX10
蛋白名称
Protoheme IX farnesyltransferase mitochondrial
别名
COX10;Protoheme IX farnesyltransferase;mitochondrial;Heme O synthase
Organism-1
Human
基因ID-1
1352
SwissProt-1
Q12887
Organism-2
Mouse
SwissProt-2
Q8CFY5
背景
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lys
细胞定位
Mitochondrion membrane; Multi-pass membrane protein.
