Connexin-26 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2613503
- 产品信息
商品描述
靶点-Target
Connexin-26
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Connexin-26. AA range:45-94
特异性
Connexin-26 Polyclonal Antibody detects endogenous levels of Connexin-26 protein.
基因名称
GJB2
蛋白名称
Gap junction beta-2 protein
别名
GJB2;Gap junction beta-2 protein;Connexin-26;Cx26
Organism-1
Human
基因ID-1
2706
SwissProt-1
P29033
Organism-2
Mouse
基因ID-2
14619
SwissProt-2
Q00977
Organism-3
Rat
基因ID-3
394266
SwissProt-3
P21994
背景
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Colocalizes with GJB4 at gap junction plaques in the cochlea. .





