Connexin-26 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613503

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商品描述
  • 靶点-Target

    Connexin-26

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    26kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Connexin-26. AA range:45-94

  • 特异性

    Connexin-26 Polyclonal Antibody detects endogenous levels of Connexin-26 protein.

  • 基因名称

    GJB2

  • 蛋白名称

    Gap junction beta-2 protein

  • 别名

    GJB2;Gap junction beta-2 protein;Connexin-26;Cx26

  • Organism-1

    Human

  • 基因ID-1

    2706

  • SwissProt-1

    P29033

  • Organism-2

    Mouse

  • 基因ID-2

    14619

  • SwissProt-2

    Q00977

  • Organism-3

    Rat

  • 基因ID-3

    394266

  • SwissProt-3

    P21994

  • 背景

    This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Colocalizes with GJB4 at gap junction plaques in the cochlea. .