FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
COMT
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
30kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human COMT. AA range:61-110
特异性
COMT Polyclonal Antibody detects endogenous levels of COMT protein.
基因名称
COMT
蛋白名称
Catechol O-methyltransferase
别名
COMT;Catechol O-methyltransferase
Organism-1
Human
基因ID-1
1312
SwissProt-1
P21964
Organism-2
Mouse
SwissProt-2
O88587
背景
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008],
细胞定位
[Isoform Soluble]: Cytoplasm .; [Isoform Membrane-bound]: Cell membrane ; Single-pass type II membrane protein ; Extracellular side .
