FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
COL4A4
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
164kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Collagen IV alpha4. AA range:541-590
特异性
COL4A4 Polyclonal Antibody detects endogenous levels of COL4A4 protein.
基因名称
COL4A4
蛋白名称
Collagen alpha-4(IV) chain
别名
COL4A4;Collagen alpha-4;IV;chain
Organism-1
Human
基因ID-1
1286
SwissProt-1
P53420
Organism-2
Mouse
SwissProt-2
Q9QZR9
背景
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix, basement membrane . Colocalizes with COL4A4 and COL4A5 in GBM, tubular basement membrane (TBM) and synaptic basal lamina (BL). .
