- 产品信息
商品描述
靶点-Target
Collagen II
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
140kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Collagen II. AA range:101-150
特异性
COL2A1 Polyclonal Antibody detects endogenous levels of COL2A1 protein.
基因名称
COL2A1
蛋白名称
Collagen alpha-1(II) chain
别名
COL2A1;Collagen alpha-1;II;chain;Alpha-1 type II collagen
Organism-1
Human
基因ID-1
1280
SwissProt-1
P02458
Organism-2
Mouse
基因ID-2
12824
SwissProt-2
P28481
Organism-3
Rat
基因ID-3
25412
SwissProt-3
P05539
背景
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix .





